What to do with all this beautiful squash around the house? I’m going to try a variation of this recipe from Whole Foods Market’s site. I love butternut squash and it’s much easier to prepare than I had imagined. Any squash can be baked in an oven at 375 for 1 to 1 1/2 hours (depending on the size). Just be sure to poke some vent holes and place on a baking sheet.